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As described, ceramides are capable of forming membrane channels in both planar phospholipid membranes and the outer membranes of isolated mitochondria, large enough to allow the passage of proteins released during mitochondrial outer membrane permeabilization (MOMP) (Fisher-Wellman et al., 2021)

In clinical practice, physicians treating patients with drug-resistant H

Pretorius E, Swanepoel AC, Buys AV, Vermeulen N, Duim W, Kell DB

Also, a direct comparison between the different approaches herein reported is difficult since they are in different development stages, with some only showing in vitro data while other strategies have already completed pre-clinical (in vivo ) testing

Krapp, S., Mimura, Y., Jefferis, R., Huber, R

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