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Oxidative stress and epigenetic regulation in ageing and age-related diseases

This broad influence helps explain the systemic effects observed in clinical studies, where single bioregulators produced improvements across multiple physiological parameters

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[49] reported that the levels of 8-isoprostaglandin F2 (one of the major isoprostanes) in serum and synovial fluid were higher in OA patients compared to control subjects

Gastroenterology 131 , 11101121 (2006)

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