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Sleep Medicine, 83, 299303

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The study showing copper peptides increased collagen in 70% of users versus 40% for retinoic acid suggests copper peptides may actually be more effective for collagen building specifically, though retinoids offer additional benefits (texture improvement, dark spot reduction) that copper peptides don't provide as strongly

This process would explain the delineation between lesional and non-lesional KP skin, while also explaining some of the variance seen in KP subtypes

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