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Malek Mahdavi, R

investigated the production of TMAO in the plasma and the urine by feeding patients an eight-ounce steak followed by a capsule of 250 mg heavy isotope-labelled L-carnitine [86]

Because nitric oxide typically decreases in response to an increase in postprandial oxidative stress [22, 35], likely mediated by the increase in superoxide production and associated endothelial dysfunction [36], maintenance of nitric oxide via carnitine ingestion could be viewed as favorable in regards to vascular function

& Powers, R

We first showed that CAR siRNA treatment was effective in reducing both CAR mRNA and protein levels when compared with siRNA control treated HepG2 cells (Figure S3c, Supplementary Information)

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