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Septic cardiomyopathy (SIC) In a model of LPS-mediated septic cardiomyopathy, some researchers revealed that LPS caused ferroptosis and septic cardiac injury by downregulating GPX4 protein levels and increasing COX-2 [93]

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The researchers were unable to identify a minimum toxic dose or a lethal dose and reported no teratogenic, genotoxic, anaphylactic, or local toxic effects

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