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Furthermore, it protects cells against oxidative stress, which plays a role in chronic inflammation and tissue damage
10.1074/jbc.M702615200 48 MetzlerK
doi: 10.4103/nrr.nrr-d-24-01417 17 ChitimusD
Ageing: somatic mutations accumulate in ageing and diseased neurons
Importantly, the N-terminal catalytic GTPase-activating domain of ArfGAP1 (contained within residues 1136), serves as a poor substrate of LRRK2 (Figure 1E), consistent with a prior study (Xiong et al., 2012)
doi: 10.1016/j.neulet.2011.08.047
