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doi: 10.1016/j.jsbmb.2019.105570
The ototoxicity of quinine is dose-dependent, with higher doses leading to more pronounced auditory disturbances
Furthermore, a recent study unveiled a significant upregulation of 4-HNE expression in lung fibroblasts isolated from PF patients, concomitant with a concurrent reduction in GPX4 levels and an elevation in 4-HNE expression observed in an in vivo model of bleomycin (BLM)-induced PF [59]
