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TMAO inhibits the expression of sirtuin 3 (SIRT3) and the activity of superoxide dismutase 2 (SOD2), leading to the accumulation of mitochondrial ROS (mtROS)

[Crossref] Jacobs R, Oldfield E (1979) Deuterium nuclear magnetic resonance investigation of dimyristoyllecithin-dipalmitoyllecithin and dimyristoyllecithin-cholesterol mixtures

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[DOI] [PubMed] [Google Scholar] 292.Seino H, Uchibori T, Nishitani T, Inamasu S

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These can include a potentially shorter overall battery lifespan if consistently pushed to its limits, increased heat generation requiring more sophisticated thermal management, and often a higher cost for batteries with superior C-rate performance