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Similar content being viewed by others Introduction Chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and mortality worldwide [1], is characterized by persistent respiratory symptoms, such as cough, sputum production, and dyspnea [2]

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[PubMed] [Google Scholar] 29.Colucci L., Bosco M., Ziello A.R., Rea R., Amenta F., Fasanaro A.M