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Depending on your genotype, this can have a modest to meaningful effect on collagen synthesis, skin repair, and cellular renewal

Huang H, Gundapuneedi T, Rao U

2014;5(11):e1515
However, the induction of necroptosis in mouse macrophages was not effectively prevented by NLRP3 inhibition (66), indicating that MSU crystals may stimulate macrophage necrosis and ensuing inflammation through various mechanisms

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