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In Poland, the incidence is higher, at around 1 in 120,000 births, with a particularly high incidence in the northern region of Pomerania, where, depending on the source, it is estimated at 1 in 20,000 or even 1 in 16,900 births

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It can modulate neuronal function and hence the hypothalamo-pituitary gonadal axis to impose its influence on female reproduction since it is widespread in the hypothalamus (Liu et al., 2004)

ADL, activities of daily living
