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Increased formation of oxidative DNA damage, 8-hydroxy-2-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes

Cao J, Schulte J, Knight A, Leslie NR, Zagozdzon A, Bronson R, Manevich Y, Beeson C, Neumann CA

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These lesions were characterized by severe proximal and distal tubular cell swelling (cell degeneration), tubular cell necrosis, and a deterioration of the architecture of the kidney

Brazilian J Med Biol Res