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5 Antioxidants The therapeutic approaches currently being explored in FRDA are focused on either increase the levels of frataxin or mitigating the out-turn of frataxin loss

cyminum contains extracts that exhibit anti-bacterial, anti-inflammatory, free radical, and pain relief effects, among others due to the phytochemical constituents such as terpenes, phenol and flavonoids (Ramya et al., 2022b

In the Baltimore Longitudinal Study of Aging that followed 579 nondemented older adults for an average of 9.3 years, daily folate intakes of at least 400 g at baseline were associated with a 55% lower risk of developing Alzheimers disease compared to lower intakes (160)
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The identification of mutations in the HFE gene and subsequent studies have reshaped diagnostic algorithms resulting in a marked reduction in the need for liver biopsy