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Compared to small molecule-based therapy, gene therapy such as viral vector-based therapies (e.g., adenovirus, lentivirus, AAV) and oligonucleotide-based therapies (e.g., mRNA, miRNA mimics, antisense oligonucleotides, siRNA) provide more interventional targets available that were, however, previously undruggable by small molecules

It is believed folic acid may play a role in reducing UV-B damage as well

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Simone BA, Champ CE, Rosenberg AL, Berger AC, Monti DA, Dicker AP, Simone NL

Some people may experience mild stomach discomfort, nausea, bloating, headache, or allergic reactions

Thus, this review will discuss the concrete evidence of fundamental experiments and epidemiological surveys to explain the possible comorbidity between periodontitis and hyperuricemia