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Exosomes are endocytosis-derived EVs with a size range of 30150 nm, whereas microvesicles range from 1001,000 nm in diameter and are formed by the plasma membrane

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Metformin affects macrophages' phenotype and improves the activity of glutathione peroxidase, superoxide dismutase, catalase and decreases malondialdehyde concentration in a partially AMPK-independent manner in LPS-stimulated human monocytes/macrophages