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Their recently discovered enrichment in two additional layers within focal adhesions and their role in regulating myosin IB and IC affinity to actin suggest they modulate the precise dynamics of adhesion formation and turnover that is needed for persistent migration

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5.5 Current status of research into the endothelial glycocalyx in sepsis Endothelial dysfunction and glycocalyx damage have become a focus of sepsis research, and markers of glycocalyx degradation are being identified

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