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10.1021/acssensors.7b00450 44
In melanoma cells, berberine induces autophagic cell death by inactivating the AKT/mTOR signaling pathway [224]
Hoekstra WG
GSH is synthesised de novo from glutamate, cysteine and glycine [13] with a -carboxyl linkage between glutamate and cysteine of GSH, which is only susceptible to hydrolysis by glutamyltranspeptidase, [14] rather than the usual -carboxyl group
L-gamma-Glutamyl-L-cysteinyl-glycine disulfide
A schematic view of the different therapeutic agents and their mechanism of actions in melasma management is represented in Figure 3
