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Loss or downregulation of E-cadherin is a common feature in many cancer types and is associated with increased invasiveness and metastasis, as reduced E-cadherin expression disrupts cell-cell adhesion, allowing cancer cells to detach from the primary tumor and invade surrounding tissues [4]

Cubilin, the endocytic receptor for intrinsic factor-vitamin B 12 complex, mediates high-density lipoprotein holoparticle endocytosis

MT-2 hits more receptors and has a broader side-effect profile

USA 96 , 1242412429 (1999)

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356 Octadecanoid endoperoxides can be created via both radical and singlet oxygen-dependent processes