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To this end, T cells from a JNK1 knockout mouse hyperproliferated, exhibited decreased activation and induced cell death and preferentially differentiated into Th2 cells [30]
Figure 4: Drug-Induced Liver Injury

doi: 10.1016/j.actbio.2019.02.031

Biochemistry (Mosc) 87, S168S177

Like other mentioned NAC meta-analyses, small sample size and high heterogeneity remained issues, and the authors concluded that larger randomized controlled trials were needed to further explore the impact of NAC on pain scores, opioid consumption, and new persistent opioid use

Habaxi et al., 2024)
