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As for the mechanism, it gets more than a bit technical, but well just say the experimenters believed that lysines antagonistic actions at a stress-promoting cell receptor called 5-HT4 was the key driver of stress-reducing effects

[1] [2] Berberine products are typically sold as food supplements in the UK, though their classification depends on the claims made and intended use

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At the same time, it is important to remark that the finding of lower C2 as risk factor for depression is highly consistent with data from other studies using clinical samples, animal models and genomic data [32, 65]