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TMAO and the inflammasome NLRP3 The activation of the NLRP3 inflammasome is a critical mediator of TMAO-induced pro-inflammatory effects

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Diabetes Care 40(9):1226-32 2017 PMC5566278 Shah AS, Maahs DM, Stafford JM, Dolan LM, Lang W, Imperatore G, Bell RA, Liese AD, Reynolds K, Pihoker C, Marcovina S, D'Agostino RB, Jr., Dabelea D

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Animal sources offer the most absorbable form

Practical Recommendations: For those focusing primarily on weight and fat loss, an L-carnitine powder, such as Gen-Tec Nutrition L-Carnitine, might be the preferred choice