vulvar melanotic macule histology macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Clinical and Dermoscopic Features of

Clockphagy is an autophagic process that selectively degrades the core circadian clock protein aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1), thereby promoting ferroptosis [212]

Evaluation of drug abuse by hair analysis and self-reported use among MSM under PrEP: results from a French substudy of the ANRS-IPERGAY trial

doi: 10.1096/fj.02-0752rev 40 Chiorcea-PaquimAM

J Oral Pathol Med

Moreover, ApoE4-expressing microglia exhibit impaired mitochondrial oxidation and lipid metabolism, contributing to a pro-inflammatory state, exacerbating AD pathology [46]

And finally, Zinc is a key mineral that fuels immune response, tissue repair and DNA synthesis