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Current studies show that treatment of cortical neurons with glutamate resulted in an increase in Bax with a decrease in Bcl-2 proteins, loss of the MMP followed by a release of cytochrome c, and activation of caspase-9, representing the classical mitochondrial apoptotic pathway ( Figure 3 )
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doi: 10.1007/978-3-319-19650-3_715 124
Importantly, ferroptosis has been shown to be exploited by RBC precursors, regulating their differentiation [40]
PMID: 145 DashkevichARaissadatiASyrjlSZarkadaGKernenMAet al
doi: 10.1016/j.heliyon.2022.e10748 106 AlahmarATSenguptaP
