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TGF-1 is an important pro-fibrotic cytokine that regulates FAO [39]

PMID: 66 KloseCSNArtisD

EP was supported by NIAAA grant K01 AA025306 and the McKnight Brain Research Foundation

Cell Cycle 14 , 28815 (2015)

To complement these in vivo efforts, in vitro studies that examine the effects of perturbing ligand-receptor interactions in specific ostegenic cell types will be valuable in providing a more complete understanding of how IGFs elicit their biological effects

Targeting mitochondrial iron metabolism suppresses tumor growth and metastasis by inducing mitochondrial dysfunction and mitophagy
