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doi:10.1016/j.tplants.2012.03.004

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In contrast, CEBPBs role in antimicrobial defense involves CEBPB binding to the hBD-2 promoter, where it suppresses basal transcription but cooperates with NF-B for LPS-induced expression [122]

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The toxins themselves or acting synergistically with other mediators, induce intestinal injury and inflammation via disruption of the intestinal epithelial barrier, induction of proinflammatory mediators and cytokines, causing cell apoptosis or necrosis in epithelial and immune cells and contributing to mucosal damage

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