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Briefly, to verify the targeted binding between miR-29b-3p and the GGCT gene, a 2000-bp DNA fragment (derived from the transcription start site of the GGCT gene) was inserted into the pmir-GLO-Basic vector to construct the wild-type pmir-GLO-GGCT-3 UTR reporter plasmid (wt) and the mutant pmir-GLO-GGCT-3 UTR reporter plasmid (mut)

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doi: 10.1016/j.canlet.2015.07.013 19 LscherWPotschkaH

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In the course of this process, hydroperoxides (ROOHs) or hydrogen peroxide (H 2 O 2 ) are converted to their respective alcohols (ROHs) or water (H 2 O), respectively