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Gene Designer: a synthetic biology tool for constructing artificial DNA segments

It will be interesting in the future to determine the extent to which DP-Ect-RhoA module works to convert mechanical cues into alterations in contractile signaling versus longer term transcriptional changes depending on actin remodeling, for instance, through the SRF/MRTF pathway, which has been demonstrated to be important for cardiac homeostasis and epidermal differentiation (48, 57, 58, 59, 60)

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Each session takes approximately 3060 minutes, and there is minimal downtime

Add-Mix-Measure proliferation with the Lumit Cell Proliferation (Human Ki-67) Assay: Increase confidence - A large assay window provides clear separation between treated and control samples Reduce lab time and effort using an easy, no-wash, add-and-read protocol Faster answers - hKi-67 levels show significant changes at earlier time points, shortening the time to decision Clearly discern between changes in proliferation and effects due to cytotoxicity Is my treatment affecting cell growth

Beta-cell function improvements, if they occurred during treatment, can persist for months beyond cessation