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Targeting iron metabolism and ferroptosis as novel therapeutic approaches in cardiovascular diseases

& Citardi, M

It can also act as an antidepressant (522)

But on top of supporting energy, getting enough B12 is required for the production and maintenance of healthy red blood cells, supporting proper neurological function, and maintaining a healthy nervous system

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However, excessive PARP1 activation, due to exposure to genotoxic agents, can dramatically reduce NAD + and ATP levels, affecting sirtuin activity and cellular homeostasis and leading to cell death