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Weeks 5-16: The ramp-up to efficacy During this phase, the dose is gradually increased every few weeks

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In a study published in the US National Library of Medicine National Institutes of Health, the many faces of a vitamin B12 deficiency was analysed

In rare cases where B12 is essential but acne remains intractable, dermatologists may consider oral isotretinoin, which in the UK can only be initiated by consultant dermatologists and requires strict monitoring, including a pregnancy prevention programme for women of childbearing potential

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