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ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

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The nuclear factor kappa B (NF-B) pathway is critical in inflammation and immune responses

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This is followed by an oxidative decarboxylation to form ribulose 5-phosphate (a five-carbon sugar): Two molecules of NADPH and one CO2 are formed for every molecule of glucose 6-phosphate that enters this pathway
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