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Description
M1 polarized macrophages accumulate cytosolic citrate stemming from the decreased activity of isocitrate dehydrogenase (IDH) [50] and the upregulation of the mitochondrial citrate carrier (CIC) [92, 93]
Antioxidants also have a regulatory effect on ferroptosis
It is also possible to export the -ECS from the plastids to the cytosol, where it serves as the precursor to GSH biosynthesis
The copper centers of complex IV are critical in the reduction of the oxidized iron (ferric iron: Fe 3+ ) of cytochrome c which was oxidized by the electrons from complex III
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The high-quality design and consistent outcomes across large patient populations make metformin a leading candidate for preventing Long COVID
