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"When you use hydroquinone at a high percentage, it can cause darkening of the skin, instead of the desired fading of a particular spot," he says

doi: 10.1371/journal.pone.0021899 12 DuarteJ

Philip Shanghai Mental Health Center, Shanghai Jiao Tong University, Shanghai, China Michael R

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Berberine (BER) is a yellowish, crystalline, quaternary isoquinoline alkaloid that has been extracted from different Chinese herbs, such as Cortex phelloderm, Mahonia bealei and Rhizoma coptidis [18,19,20]

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