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Similar content being viewed by others Introduction Alzheimers disease (AD) is a chronic, neurodegenerative disease and the leading cause of dementia, affecting more than 50 million people worldwide

Harmonic restraints of 50.0 kcal mol 1 2 were applied to the solutes, including the crystallographic ions, to allow solvent relaxation while preserving the maximum fidelity to the docking pose, and the Andersen temperature coupling scheme 81,82 was used to control and equalize the temperature

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While iodine is essential for thyroid function and overall well-being, an imbalance, whether deficiency or excess, can lead to significant health consequences