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7 Compared with placebo, patients taking metformin had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years)

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Bax promotes death

In this biological context, natural compounds with antioxidant and anti-inflammatory properties have attracted growing interest as complementary strategies to modulate redox homeostasis, immune signaling, and mitochondrial function in ASD

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Mitochondrial energy supply, inflammation levels and intracellular oxidative stress are key mechanisms in the pathogenesis of HF (64)