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Inflammatory cytokines can cross the blood-brain barrier, activating microglial cells (the brain's resident immune cells)

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CahillGFJr.Fuel metabolism in starvation

In addition, obese mice fed high carbohydrate diets can exacerbate skeletal muscle damage in sepsis (49)

L-carnitine enhances resistance to oxidative stress by reducing DNA damage in Ataxia telangiectasia cells