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It can be converted to NAM by NAD + -dependent enzymes or to nicotinamide adenine dinucleotide phosphate (NADP + ) by NAD kinase (NADK) for de novo NADP synthesis[9, 10]

Categorical data were compared using Fishers exact test when two groups were compared or, otherwise, a Chi-squared test

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MS-153 We have recently reported that a synthetic compound, (R)-()-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153) reduced alcohol intake in male P rats (Alhaddad et al., Conclusion and closing thoughts Alcohol consumption affects a number of neurotransmitters and neuromodulators in the CNS, including dopamine, serotonin and GABA