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Stable for 18+ months as dry powder

[DOI] [PubMed] [Google Scholar] 64.Cai J, Chen Y, Seth S, Furukawa S, Compans RW, Jones DP

The potential of CD38-targeting sdAbs has been explored through the creation of different structures, such as chimeric antibodies, biparatopic antibodies, heavy chain-only antibodies, and half-life-extended nano-BiKEs, which show promise for the treatment of MM

Adipose tissues release numerous metabolic hormones, cytokines, and other mediators, such as glycerol, leptin, adiponectin, and nonesterified fatty acids (NEFAs) [6]

All of those things generate oxidative stress
Further studies are needed to assess the frequency of such mutations among patients and explore ways to inhibit its activity and restore sensitivity to hormonal therapy [51]
