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463 Recently, a research identified that in human corneal epithelial cells exposed to hyperosmotic stress, mtDNA passed through the mPTP pore and was released to the cytoplasm, which activates the cGAS-STING pathway and aggravates inflammation
Nrf2 also regulates the expression of genes that control inflammatory and immune system responses (Kasprzak et al., 2020)
Matsuzaki, T
Patrick, M
For example, it has been demonstrated that melatonin can bind several target proteins, including enzymes, receptors, pores, and transporters [17]
L-glutathione shields the skin from UV-induced oxidative stress and the accelerated signs of skin ageing such as wrinkles and fine lines
