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Increased ROS levels in cancer cells have the capacity to suppress the activity of mitogen-activated protein kinase (MAPK), protein tyrosine phosphatases (PTPs), phosphatases, and tensin homolog (PTEN), which in turn may promote both cell proliferation and survival (Moloney And Cotter 2018)

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Ritchie, R

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An oral lead-in phase is used to confirm that the patient can tolerate the drug safely

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