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Hippocampal neurons were then cultured a further 3-7 days, at which time they were either transfected or treated with various pharmacological reagents as described in (Wayman et al., 2008)

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This segment delves into the function of the HGF/c-MET pathway and its subsequent routes in the TME post-activation, encapsulating its impact on various TME cells, as detailed in Table 1

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At higher doses, side effects can be dangerous and life-threatening, such as seizures, loss of consciousness, depression of respiratory and circulatory centers, slow heart rate, and even cardiac arrest

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