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Salama and Al-Mutawa (2009) described the roles of GSH as ROS scavenger in the improvement of salt stress tolerance

Berberine, an isoquinoline alkaloid from Berberis spp., has demonstrated promising antioxidant activity via promoting heme oxygenase-1 (HO-1) expression, activating Nrf2/AMPK/SIRT1 signaling, inhibiting the NLRP3 inflammasome, balancing glutathione levels, and regulating mitochondrial redox processes (Sunhe et al., 2024

In other words, an adequate supply of antioxidants allows normal processes mediated by ROS, such as the destruction of infection-causing bacteria, to occur without negative effects on body cells

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Furthermore, its ability to modulate tumor cell migration and invasion, particularly through the regulation of EMT and mitochondrial fusion

In the future, clinical studies on diet and PD need to conduct more large-scale long-term cohort studies and randomized controlled trials to explore the relationship between diet and PD in greater depth and provide more scientific evidence for proposing PD-related diet intervention strategies and preventing and treating PD using nonpharmacological means