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There is evidence in other cancer types that point towards using wildtype IDH1 inhibition in combination with chemotherapy as a strategy for treatment, although these studies focused on redox balance and ROS (Vaziri-Gohar et al., 2022

Oxidative stress can render tumor cells insensitive to anti-proliferative signals, apoptosis, and anchorage-independent growth, which alters tumor cell invasion and migration through epigenetic and metabolic mechanisms, further contributing to colorectal cancer development and progression (Ziczuk et al., 2020)

Dies geschieht mithilfe von Aminosuren Lysin und Methionin

Eslamian G, Amirjannati N, Noori N, Sadeghi MR, Hekmatdoost A

Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis

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