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Description
AOD-9604 and GLP-1 agonists like Semaglutide or Tirzepatide work through fundamentally different mechanisms with very different efficacy profiles
A Phase 2 study published in the New England Journal of Medicine in 2023 (Jastreboff et al.) reported substantial weight loss in participants with obesity
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This approach supports more complex signalling and receptor studies while reducing variability compared to testing each peptide independently
Nature (2014) 4
Rebooting this cycle is demanding
