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A similar protective action was observed for Bacteroides fragilis- derived phenylpropionate in pigs, activating AhR signaling and maintaining the integrity of the intestinal epithelial barrier (65)

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Targeting these mechanisms may result in novel therapeutic approaches aimed at developing the means of effective prevention and treatment of the core ASD symptoms [11]

This effect was mediated by growth arrest and DNA damage-inducible gene 34 (GADD34) induction, a protein known to inhibit eIF2 phosphorylation

Abo-Ghanema II, El-Nasharty MA, El-Far AH, Ghonium HA

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