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The biochemical assays revealed that abemaciclib hindered the progression of breast cancer cells MDA-MB-231 and MCF-7 and enhanced RT (10 Gy) by provoking cell cycle arrest throughout the restraint of CDK4 and CDK6 expression and increasing apoptosis, in addition to decreasing the PI3K/AKT/mTOR and NF-/TGF- pathway expression

This was followed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) for detection

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doi: 10.1007/BF00965511

[12] has shown that the powders of pumpkin and bitter gourd peel, meat, and seeds can reduce blood glucose levels in rat models