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The modulation of c-MET pathway activity by TGF- allows to speculate that subsets of patients with glioblastoma would have responded to TGF- inhibitors such as galunisertib (LY2157299 monohydrate) with an increase of c-MET activity and potentially MET-mediated migration and invasion

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(2008) An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Control culture variables that affect signaling: Passage number, confluence, serum concentration, extracellular matrix coating, oxygen condition, mycoplasma status, baseline cell health, and image-analysis thresholds can all influence FAK phosphorylation, VEGFR2 readouts, and tube-formation results