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doi: 10.3389/fphar.2023.1230783

The supernatants were collected and used for analysis

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Additionally, NAD is a substrate for ADP-ribosyltransferases, which catalyze ADP-ribose transfer reactions, converting NAD into nicotinamide and ADP-ribosylated products ()

This is especially important for patients on bupropion, where consistency in tirzepatide dosing translates directly to consistency in the side effect profile and predictability in the seizure risk calculation