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10.1016/s1535-6108(03)00050-3 27 DuJ.ZhuX.ZhangY.HuangX.WangX.YangF.et al (2024)

The use of targeted nanocarriers solves the problems of both insufficient brain penetration of hydrophilic therapeutic molecules and high treatment doses inducing side-effects at the periphery [21, 26]

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and particles in the range of 13 m are suitable for deposition in the distal part of the fine bronchioles

The difference lies in their formulations