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When activated, mast cells release a cascade of inflammatory mediators, including: This can disrupt the BBB, promote leukocyte infiltration, and create a pro-inflammatory CNS microenvironment
This is why attempting to maintain constant blood levels is both unnecessary and potentially wasteful
That word of mouth is now unstoppable
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Eur J Appl Physiol Occup Physiol 57: 120125, 1988
