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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Ebrahimi M, Teymouri K, Chen CC, Mohiuddin AG, Pouget JG, Goncalves VF, Tiwari AK, Zai CC, Kennedy JL

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Adenosine A 2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway

Because FBP is an allosteric activator of the end-step glycolytic enzyme pyruvate kinase, the increase in its level has been viewed as means to promote cancer cell glycolysis

Therefore, depending on the specific C.acnes subtype, the effect on skin cells might be beneficial or detrimental